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A Framework for Multiple Kernel Support Vector Regression and Its Applications to siRNA Efficacy Prediction

The cell defense mechanism of RNA interference has applications in gene function analysis and promising potentials in human disease therapy. To effectively silence a target gene, it is desirable to select appropriate initiator siRNA molecules having satisfactory silencing capabilities. Computational...

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Détails bibliographiques
Publié dans:IEEE/ACM Trans Comput Biol Bioinform
Auteurs principaux: Qiu, Shibin, Lane, Terran
Format: Artigo
Langue:Inglês
Publié: 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4669230/
https://ncbi.nlm.nih.gov/pubmed/19407344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1109/TCBB.2008.139
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