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Predicting siRNA efficacy based on multiple selective siRNA representations and their combination at score level

Small interfering RNAs (siRNAs) may induce to targeted gene knockdown, and the gene silencing effectiveness relies on the efficacy of the siRNA. Therefore, the task of this paper is to construct an effective siRNA prediction method. In our work, we try to describe siRNA from both quantitative and qu...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: He, Fei, Han, Ye, Gong, Jianting, Song, Jiazhi, Wang, Han, Li, Yanwen
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5357899/
https://ncbi.nlm.nih.gov/pubmed/28317874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep44836
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