Predicting siRNA efficacy based on multiple selective siRNA representations and their combination at score level

Small interfering RNAs (siRNAs) may induce to targeted gene knockdown, and the gene silencing effectiveness relies on the efficacy of the siRNA. Therefore, the task of this paper is to construct an effective siRNA prediction method. In our work, we try to describe siRNA from both quantitative and qu...

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Udgivet i:Sci Rep
Main Authors: He, Fei, Han, Ye, Gong, Jianting, Song, Jiazhi, Wang, Han, Li, Yanwen
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5357899/
https://ncbi.nlm.nih.gov/pubmed/28317874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep44836
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