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Predicting siRNA efficacy based on multiple selective siRNA representations and their combination at score level

Small interfering RNAs (siRNAs) may induce to targeted gene knockdown, and the gene silencing effectiveness relies on the efficacy of the siRNA. Therefore, the task of this paper is to construct an effective siRNA prediction method. In our work, we try to describe siRNA from both quantitative and qu...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: He, Fei, Han, Ye, Gong, Jianting, Song, Jiazhi, Wang, Han, Li, Yanwen
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5357899/
https://ncbi.nlm.nih.gov/pubmed/28317874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep44836
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