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Structural roles of CTG repeats in slippage expansion during DNA replication

CTG triplet repeat sequences have been found to form slipped-strand structures leading to self-expansion during DNA replication. The lengthening of these repeats causes the onset of neurodegenerative diseases, such as myotonic dystrophy. In this study, electrophoretic and NMR spectroscopic studies h...

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Détails bibliographiques
Auteurs principaux: Chi, Lai Man, Lam, Sik Lok
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2005
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1065260/
https://ncbi.nlm.nih.gov/pubmed/15767285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki307
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