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The origin of genetic instability in CCTG repeats

CCTG tetranucleotide repeat expansion is associated with a hereditary neurological disease called myotonic dystrophy type 2 (DM2). The underlying reasons that lead to genetic instability and thus repeat expansion during DNA replication remains elusive. Here, we have shown CCTG repeats have a high pr...

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Detalhes bibliográficos
Main Authors: Lam, Sik Lok, Wu, Feng, Yang, Hao, Chi, Lai Man
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3152338/
https://ncbi.nlm.nih.gov/pubmed/21478167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr185
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