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The competing mini-dumbbell mechanism: new insights into CCTG repeat expansion

CCTG repeat expansions in intron 1 of the cellular nucleic acid-binding protein gene are associated with myotonic dystrophy type 2. Recently, we have reported a novel mini-dumbbell (MDB) structure formed by two CCTG or TTTA repeats, which potentially has a critical role in repeat expansions. Here we...

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Publicat a:Signal Transduct Target Ther
Autors principals: Guo, Pei, Lam, Sik Lok
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5661647/
https://ncbi.nlm.nih.gov/pubmed/29263904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sigtrans.2016.28
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