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Structural roles of CTG repeats in slippage expansion during DNA replication
CTG triplet repeat sequences have been found to form slipped-strand structures leading to self-expansion during DNA replication. The lengthening of these repeats causes the onset of neurodegenerative diseases, such as myotonic dystrophy. In this study, electrophoretic and NMR spectroscopic studies h...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2005
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1065260/ https://ncbi.nlm.nih.gov/pubmed/15767285 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki307 |
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