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Interleukin-18: a therapeutic target in rheumatoid arthritis?

Interleukin 18 (IL-18), a member of the IL-1 superfamily of cytokines has been demonstrated to be an important mediator of both innate and adaptive immune responses. Several reports have implicated its role in the pathogenesis of rheumatoid arthritis (RA). Although biologic therapy is firmly establi...

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Detalhes bibliográficos
Main Authors: McInnes, Iain B, Liew, Foo Y, Gracie, J Alastair
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1064903/
https://ncbi.nlm.nih.gov/pubmed/15642152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar1497
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