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Interleukin-18: a therapeutic target in rheumatoid arthritis?

Interleukin 18 (IL-18), a member of the IL-1 superfamily of cytokines has been demonstrated to be an important mediator of both innate and adaptive immune responses. Several reports have implicated its role in the pathogenesis of rheumatoid arthritis (RA). Although biologic therapy is firmly establi...

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Библиографические подробности
Главные авторы: McInnes, Iain B, Liew, Foo Y, Gracie, J Alastair
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2005
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1064903/
https://ncbi.nlm.nih.gov/pubmed/15642152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar1497
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