A proinflammatory role for IL-18 in rheumatoid arthritis

IL-18 is a novel cytokine with pleiotropic activities critical to the development of T-helper 1 (Th1) responses. We detected IL-18 mRNA and protein within rheumatoid arthritis (RA) synovial tissues in significantly higher levels than in osteoarthritis controls. Similarly, IL-18 receptor expression w...

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Autori principali: Gracie, J. Alastair, Forsey, Rosalyn J., Chan, Woon Ling, Gilmour, Ashley, Leung, Bernard P., Greer, Morag R., Kennedy, Kristy, Carter, Robert, Wei, Xiao-Qing, Xu, Damo, Field, Max, Foulis, Alan, Liew, Foo Y., McInnes, Iain B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 1999
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC409841/
https://ncbi.nlm.nih.gov/pubmed/10562301
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