IL-33 reduces the development of atherosclerosis

Atherosclerosis is a chronic inflammatory disease of the vasculature commonly leading to myocardial infarction and stroke. We show that IL-33, which is a novel IL-1–like cytokine that signals via ST2, can reduce atherosclerosis development in ApoE(−/−) mice on a high-fat diet. IL-33 and ST2 are pres...

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Detalhes bibliográficos
Main Authors: Miller, Ashley M., Xu, Damo, Asquith, Darren L., Denby, Laura, Li, Yubin, Sattar, Naveed, Baker, Andrew H., McInnes, Iain B., Liew, Foo Y.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2008
Assuntos:
Brief Definitive Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2271006/
https://ncbi.nlm.nih.gov/pubmed/18268038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20071868
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