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Interleukin-18: a therapeutic target in rheumatoid arthritis?

Interleukin 18 (IL-18), a member of the IL-1 superfamily of cytokines has been demonstrated to be an important mediator of both innate and adaptive immune responses. Several reports have implicated its role in the pathogenesis of rheumatoid arthritis (RA). Although biologic therapy is firmly establi...

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Autores principales: McInnes, Iain B, Liew, Foo Y, Gracie, J Alastair
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2005
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1064903/
https://ncbi.nlm.nih.gov/pubmed/15642152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar1497
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