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Interleukin-18: a therapeutic target in rheumatoid arthritis?

Interleukin 18 (IL-18), a member of the IL-1 superfamily of cytokines has been demonstrated to be an important mediator of both innate and adaptive immune responses. Several reports have implicated its role in the pathogenesis of rheumatoid arthritis (RA). Although biologic therapy is firmly establi...

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Bibliographic Details
Main Authors: McInnes, Iain B, Liew, Foo Y, Gracie, J Alastair
Format: Artigo
Language:Inglês
Published: BioMed Central 2005
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1064903/
https://ncbi.nlm.nih.gov/pubmed/15642152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar1497
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