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Interleukin-18: a therapeutic target in rheumatoid arthritis?

Interleukin 18 (IL-18), a member of the IL-1 superfamily of cytokines has been demonstrated to be an important mediator of both innate and adaptive immune responses. Several reports have implicated its role in the pathogenesis of rheumatoid arthritis (RA). Although biologic therapy is firmly establi...

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Détails bibliographiques
Auteurs principaux: McInnes, Iain B, Liew, Foo Y, Gracie, J Alastair
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2005
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1064903/
https://ncbi.nlm.nih.gov/pubmed/15642152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar1497
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