The androgen receptor CAG repeat polymorphism and modification of breast cancer risk in BRCA1 and BRCA2 mutation carriers

INTRODUCTION: The androgen receptor (AR) gene exon 1 CAG repeat polymorphism encodes a string of 9–32 glutamines. Women with germline BRCA1 mutations who carry at least one AR allele with 28 or more repeats have been reported to have an earlier age at onset of breast cancer. METHODS: A total of 604...

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Bibliografiset tiedot
Päätekijät: Spurdle, Amanda B, Antoniou, Antonis C, Duffy, David L, Pandeya, Nirmala, Kelemen, Livia, Chen, Xiaoqing, Peock, Susan, Cook, Margaret R, Smith, Paula L, Purdie, David M, Newman, Beth, Dite, Gillian S, Apicella, Carmel, Southey, Melissa C, Giles, Graham G, Hopper, John L, Chenevix-Trench, Georgia, Easton, Douglas F
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2005
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1064126/
https://ncbi.nlm.nih.gov/pubmed/15743497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr971
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