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After BRCA1 and BRCA2—What Next? Multifactorial Segregation Analyses of Three-Generation, Population-Based Australian Families Affected by Female Breast Cancer

Mutations in BRCA1 and BRCA2 that cause a dominantly inherited high risk of female breast cancer seem to explain only a small proportion of the aggregation of the disease. To study the possible additional genetic components, we conducted single-locus and two-locus segregation analyses, with and with...

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Detalhes bibliográficos
Main Authors: Cui, Jisheng, Antoniou, Antonis C., Dite, Gillian S., Southey, Melissa C., Venter, Deon J., Easton, Douglas F., Giles, Graham G., McCredie, Margaret R. E., Hopper, John L.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society of Human Genetics 2001
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1235275/
https://ncbi.nlm.nih.gov/pubmed/11133358
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