An international initiative to identify genetic modifiers of cancer risk in BRCA1 and BRCA2 mutation carriers: the Consortium of Investigators of Modifiers of BRCA1 and BRCA2 (CIMBA)

BRCA1 and BRCA2 mutations exhibit variable penetrance that is likely to be accounted for, in part, by other genetic factors among carriers. However, studies aimed at identifying these factors have been limited in size and statistical power, and have yet to identify any convincingly validated modifie...

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Détails bibliographiques
Auteurs principaux: Chenevix-Trench, Georgia, Milne, Roger L, Antoniou, Antonis C, Couch, Fergus J, Easton, Douglas F, Goldgar, David E
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2007
Sujets:
Commentary
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1868919/
https://ncbi.nlm.nih.gov/pubmed/17466083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr1670
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