Breast Cancer Risk for Noncarriers of Family-Specific BRCA1 and BRCA2 Mutations: Findings From the Breast Cancer Family Registry

PURPOSE: Women with germline BRCA1 and BRCA2 mutations have five- to 20-fold increased risks of developing breast and ovarian cancer. A recent study claimed that women testing negative for their family-specific BRCA1 or BRCA2 mutation (noncarriers) have a five-fold increased risk of breast cancer. W...

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Detalhes bibliográficos
Main Authors: Kurian, Allison W., Gong, Gail D., John, Esther M., Johnston, David A., Felberg, Anna, West, Dee W., Miron, Alexander, Andrulis, Irene L., Hopper, John L., Knight, Julia A., Ozcelik, Hilmi, Dite, Gillian S., Apicella, Carmel, Southey, Melissa C., Whittemore, Alice S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Clinical Oncology 2011
Assuntos:
Original Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3236651/
https://ncbi.nlm.nih.gov/pubmed/22042950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2010.34.4440
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