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Breast Cancer Risk for Noncarriers of Family-Specific BRCA1 and BRCA2 Mutations: Findings From the Breast Cancer Family Registry

PURPOSE: Women with germline BRCA1 and BRCA2 mutations have five- to 20-fold increased risks of developing breast and ovarian cancer. A recent study claimed that women testing negative for their family-specific BRCA1 or BRCA2 mutation (noncarriers) have a five-fold increased risk of breast cancer. W...

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Main Authors: Kurian, Allison W., Gong, Gail D., John, Esther M., Johnston, David A., Felberg, Anna, West, Dee W., Miron, Alexander, Andrulis, Irene L., Hopper, John L., Knight, Julia A., Ozcelik, Hilmi, Dite, Gillian S., Apicella, Carmel, Southey, Melissa C., Whittemore, Alice S.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society of Clinical Oncology 2011
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3236651/
https://ncbi.nlm.nih.gov/pubmed/22042950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2010.34.4440
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