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Performance of Prediction Models for BRCA Mutation Carriage in Three Racial/Ethnic Groups: Findings from the Northern California Breast Cancer Family Registry

PURPOSE: Patients with early-onset breast and/or ovarian cancer frequently wish to know if they inherited a mutation in one of the cancer susceptibility genes, BRCA1 or BRCA2. Accurate carrier prediction models are needed to target costly testing. Two widely used models, BRCAPRO and BOADICEA, were d...

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Detaylı Bibliyografya
Asıl Yazarlar: Kurian, Allison W., Gong, Gail D., John, Esther M., Miron, Alexander, Felberg, Anna, Phipps, Amanda I., West, Dee W., Whittemore, Alice S.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2009
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2706699/
https://ncbi.nlm.nih.gov/pubmed/19336551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-08-1090
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