An Escherichia coli Expression Assay and Screen for Human Immunodeficiency Virus Protease Variants with Decreased Susceptibility to Indinavir

We have developed a recombinant Escherichia coli screening system for the rapid detection and identification of amino acid substitutions in the human immunodeficiency virus (HIV) protease associated with decreased susceptibility to the protease inhibitor indinavir (MK-639; Merck & Co.). The assay de...

Ausführliche Beschreibung

Bibliografische Detailangaben

Veröffentlicht in:	Antimicrob Agents Chemother
Hauptverfasser:	Melnick, Laurence, Yang, Shiow-Shong, Rossi, Rick, Zepp, Charlie, Heefner, Donald
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1998
Schlagworte:	Antiviral Agents
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC106031/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9835523/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.12.3256
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!