An Escherichia coli Expression Assay and Screen for Human Immunodeficiency Virus Protease Variants with Decreased Susceptibility to Indinavir

We have developed a recombinant Escherichia coli screening system for the rapid detection and identification of amino acid substitutions in the human immunodeficiency virus (HIV) protease associated with decreased susceptibility to the protease inhibitor indinavir (MK-639; Merck & Co.). The assay de...

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書目詳細資料

發表在:	Antimicrob Agents Chemother
Principais autores:	Melnick, Laurence, Yang, Shiow-Shong, Rossi, Rick, Zepp, Charlie, Heefner, Donald
格式:	Artigo
語言:	Inglês
出版:	American Society for Microbiology (ASM) 1998
主題:	Antiviral Agents
在線閱讀:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC106031/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9835523/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.12.3256
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