Structure-Based Design of Novel Dihydroalkoxybenzyloxopyrimidine Derivatives as Potent Nonnucleoside Inhibitors of the Human Immunodeficiency Virus Reverse Transcriptase

Two highly potent dihydroalkoxybenzyloxopyrimidine (DABO) derivatives targeting the nonnucleoside inhibitor (NNI) binding site of human immunodeficiency virus (HIV) reverse transcriptase (RT) have been designed based on the structure of the NNI binding pocket and tested for anti-HIV activity. Our le...

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Detaylı Bibliyografya

Yayımlandı:	Antimicrob Agents Chemother
Asıl Yazarlar:	Sudbeck, Elise A., Mao, Chen, Vig, Rakesh, Venkatachalam, T. K., Tuel-Ahlgren, Lisa, Uckun, Fatih M.
Materyal Türü:	Artigo
Dil:	Inglês
Baskı/Yayın Bilgisi:	American Society for Microbiology (ASM) 1998
Konular:	Antiviral Agents
Online Erişim:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC106026/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9835518/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.12.3225
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