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Coresistance to Zidovudine and Foscarnet Is Associated with Multiple Mutations in the Human Immunodeficiency Virus Type 1 Reverse Transcriptase
Human immunodeficiency virus type 1 (HIV-1) isolates obtained from a patient with AIDS were assessed for coresistance to foscarnet and zidovudine. An HIV-1 strain (AP20) coresistant to foscarnet and zidovudine was isolated after 20 months of continuous combination therapy. The reverse transcriptase...
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Hauptverfasser: | , , |
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Format: | Artigo |
Sprache: | Inglês |
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American Society for Microbiology
1998
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Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC105992/ https://ncbi.nlm.nih.gov/pubmed/9797252 |
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