Coresistance to Zidovudine and Foscarnet Is Associated with Multiple Mutations in the Human Immunodeficiency Virus Type 1 Reverse Transcriptase

Human immunodeficiency virus type 1 (HIV-1) isolates obtained from a patient with AIDS were assessed for coresistance to foscarnet and zidovudine. An HIV-1 strain (AP20) coresistant to foscarnet and zidovudine was isolated after 20 months of continuous combination therapy. The reverse transcriptase...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Tachedjian, Gilda, French, Martyn, Mills, John
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1998
Soggetti:	Antiviral Agents
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC105992/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9797252/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.11.3038
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