Killing of Staphylococcus aureus by C-8-Methoxy Fluoroquinolones

C-8-methoxy fluoroquinolones were more lethal than C-8-bromine, C-8-ethoxy, and C-8-H derivatives for Staphylococcus aureus, especially when topoisomerase IV was resistant. The methoxy group also increased lethality against wild-type cells when protein synthesis was inhibited. These properties encou...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Zhao, Xilin, Wang, Jian-Ying, Xu, Chen, Dong, Yuzhi, Zhou, Jianfeng, Domagala, John, Drlica, Karl
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1998
Assuntos:	Mechanisms of Resistance
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC105579/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9559820/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.4.956
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