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Mutant Prevention Concentration as a Measure of Antibiotic Potency: Studies with Clinical Isolates of Mycobacterium tuberculosis

The mutant prevention concentration (MPC) of a C-8-methoxy fluoroquinolone exhibited a narrow distribution for 14 genetically diverse clinical isolates of Mycobacterium tuberculosis, indicating that results from single-isolate studies are likely to be representative. When one isolate was challenged...

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Bibliografische gegevens
Hoofdauteurs: Dong, Yuzhi, Zhao, Xilin, Kreiswirth, Barry N., Drlica, Karl
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2000
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC90115/
https://ncbi.nlm.nih.gov/pubmed/10952625
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