Mutant Prevention Concentration as a Measure of Antibiotic Potency: Studies with Clinical Isolates of Mycobacterium tuberculosis

The mutant prevention concentration (MPC) of a C-8-methoxy fluoroquinolone exhibited a narrow distribution for 14 genetically diverse clinical isolates of Mycobacterium tuberculosis, indicating that results from single-isolate studies are likely to be representative. When one isolate was challenged...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Dong, Yuzhi, Zhao, Xilin, Kreiswirth, Barry N., Drlica, Karl
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2000
Assuntos:	Susceptibility
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90115/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10952625/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.44.9.2581-2584.2000
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