Killing of Staphylococcus aureus by C-8-Methoxy Fluoroquinolones

C-8-methoxy fluoroquinolones were more lethal than C-8-bromine, C-8-ethoxy, and C-8-H derivatives for Staphylococcus aureus, especially when topoisomerase IV was resistant. The methoxy group also increased lethality against wild-type cells when protein synthesis was inhibited. These properties encou...

Disgrifiad llawn

Manylion Llyfryddiaeth

Cyhoeddwyd yn:	Antimicrob Agents Chemother
Prif Awduron:	Zhao, Xilin, Wang, Jian-Ying, Xu, Chen, Dong, Yuzhi, Zhou, Jianfeng, Domagala, John, Drlica, Karl
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	American Society for Microbiology (ASM) 1998
Pynciau:	Mechanisms of Resistance
Mynediad Ar-lein:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC105579/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9559820/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.4.956
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