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Targeted elimination of zygotic messages in Xenopus laevis embryos by modified oligonucleotides possessing terminal cationic linkages
We have designed a new class of modified antisense oligodeoxyribonucleotides (ODN) consisting of a central contiguous stretch of 6–8 unmodified nucleotides flanked by 3′- and 5′-regions containing several nucleotides joined by cationic internucleoside linkages. The positive charge results from modif...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
2000
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC105372/ https://ncbi.nlm.nih.gov/pubmed/10773085 |
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