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Understanding oligonucleotide-mediated inhibition of gene expression in Xenopus laevis oocytes

Triplex-forming oligonucleotides (TFOs) modified with N,N-diethylethylenediamine can inhibit the expression of a reporter plasmid in Xenopus oocytes if the triplex is preformed prior to injection while unmodified oligonucleotides cannot. Here we show that merely forming a triplex in a reporter plasm...

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Bibliografiske detaljer
Main Authors: Bailey, Cheryl, Weeks, Daniel L.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2000
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC102614/
https://ncbi.nlm.nih.gov/pubmed/10666457
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