Understanding oligonucleotide-mediated inhibition of gene expression in Xenopus laevis oocytes
Triplex-forming oligonucleotides (TFOs) modified with N,N-diethylethylenediamine can inhibit the expression of a reporter plasmid in Xenopus oocytes if the triplex is preformed prior to injection while unmodified oligonucleotides cannot. Here we show that merely forming a triplex in a reporter plasm...
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| Veröffentlicht in: | Nucleic Acids Res |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2000
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| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC102614/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10666457/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/28.5.1154 |
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