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Expression of Noncovalent Hepatitis C Virus Envelope E1-E2 Complexes Is Not Required for the Induction of Antibodies with Neutralizing Properties following DNA Immunization

Interactive glycoproteins present on the surface of viral particles represent the main target of neutralizing antibodies. The ability of DNA vaccination to induce antibodies directed at such structures was investigated by using eight different expression plasmids engineered either to favor or to pre...

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Bibliografiske detaljer
Udgivet i:J Virol
Principais autores: Fournillier, A., Depla, E., Karayiannis, P., Vidalin, O., Maertens, G., Trépo, C., Inchauspé, G.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1999
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC104276/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10438839/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.9.7497-7504.1999
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