Expression of Noncovalent Hepatitis C Virus Envelope E1-E2 Complexes Is Not Required for the Induction of Antibodies with Neutralizing Properties following DNA Immunization

Interactive glycoproteins present on the surface of viral particles represent the main target of neutralizing antibodies. The ability of DNA vaccination to induce antibodies directed at such structures was investigated by using eight different expression plasmids engineered either to favor or to pre...

Ausführliche Beschreibung

Bibliografische Detailangaben

Veröffentlicht in:	J Virol
Hauptverfasser:	Fournillier, A., Depla, E., Karayiannis, P., Vidalin, O., Maertens, G., Trépo, C., Inchauspé, G.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1999
Schlagworte:	Pathogenesis and Immunity
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC104276/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10438839/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.9.7497-7504.1999
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