Expression of Noncovalent Hepatitis C Virus Envelope E1-E2 Complexes Is Not Required for the Induction of Antibodies with Neutralizing Properties following DNA Immunization

Interactive glycoproteins present on the surface of viral particles represent the main target of neutralizing antibodies. The ability of DNA vaccination to induce antibodies directed at such structures was investigated by using eight different expression plasmids engineered either to favor or to pre...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Fournillier, A., Depla, E., Karayiannis, P., Vidalin, O., Maertens, G., Trépo, C., Inchauspé, G.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1999
Assuntos:	Pathogenesis and Immunity
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC104276/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10438839/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.9.7497-7504.1999
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