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DNA-based immunization with chimeric vectors for the induction of immune responses against the hepatitis C virus nucleocapsid.

Vectors expressing the first 58 amino acids of the hepatitis C virus (HCV) nucleocapsid alone or as a fusion protein with the middle (pre-S2 and S) or major (S) surface antigens of hepatitis B virus (HBV) were constructed. Intramuscular immunization of BALB/c mice with the chimeric constructs in the...

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Detalhes bibliográficos
Publicado no:J Virol
Principais autores: Major, M E, Vitvitski, L, Mink, M A, Schleef, M, Whalen, R G, Trépo, C, Inchauspé, G
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC189445/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7637024/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.9.5798-5805.1995
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