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A Replication-Incompetent Adenovirus Vector with the Preterminal Protein Gene Deleted Efficiently Transduces Mouse Ears

Adenoviruses offer great potential as gene therapy agents but are limited by the strong inflammatory response that occurs in response to the recombinant virus. Since the degree of inflammation correlates in part with the potential of the viral vector for replication, we constructed a preterminal pro...

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Detalles Bibliográficos
Publicado en:J Virol
Autores principales: Moorhead, John W., Clayton, Gerald H., Smith, Roderic L., Schaack, Jerome
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 1999
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC103924/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9882305/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.2.1046-1053.1999
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