A Replication-Incompetent Adenovirus Vector with the Preterminal Protein Gene Deleted Efficiently Transduces Mouse Ears

Adenoviruses offer great potential as gene therapy agents but are limited by the strong inflammatory response that occurs in response to the recombinant virus. Since the degree of inflammation correlates in part with the potential of the viral vector for replication, we constructed a preterminal pro...

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Bibliografische Detailangaben

Veröffentlicht in:	J Virol
Hauptverfasser:	Moorhead, John W., Clayton, Gerald H., Smith, Roderic L., Schaack, Jerome
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1999
Schlagworte:	Gene Therapy
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC103924/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9882305/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.2.1046-1053.1999
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