A Replication-Incompetent Adenovirus Vector with the Preterminal Protein Gene Deleted Efficiently Transduces Mouse Ears

Adenoviruses offer great potential as gene therapy agents but are limited by the strong inflammatory response that occurs in response to the recombinant virus. Since the degree of inflammation correlates in part with the potential of the viral vector for replication, we constructed a preterminal pro...

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Pubblicato in:	J Virol
Autori principali:	Moorhead, John W., Clayton, Gerald H., Smith, Roderic L., Schaack, Jerome
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1999
Soggetti:	Gene Therapy
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC103924/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9882305/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.2.1046-1053.1999
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