A Replication-Incompetent Adenovirus Vector with the Preterminal Protein Gene Deleted Efficiently Transduces Mouse Ears

Adenoviruses offer great potential as gene therapy agents but are limited by the strong inflammatory response that occurs in response to the recombinant virus. Since the degree of inflammation correlates in part with the potential of the viral vector for replication, we constructed a preterminal pro...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Moorhead, John W., Clayton, Gerald H., Smith, Roderic L., Schaack, Jerome
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1999
Assuntos:	Gene Therapy
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC103924/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9882305/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.2.1046-1053.1999
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