A Replication-Incompetent Adenovirus Vector with the Preterminal Protein Gene Deleted Efficiently Transduces Mouse Ears

Adenoviruses offer great potential as gene therapy agents but are limited by the strong inflammatory response that occurs in response to the recombinant virus. Since the degree of inflammation correlates in part with the potential of the viral vector for replication, we constructed a preterminal pro...

Полное описание

Библиографические подробности

Опубликовано в::	J Virol
Главные авторы:	Moorhead, John W., Clayton, Gerald H., Smith, Roderic L., Schaack, Jerome
Формат:	Artigo
Язык:	Inglês
Опубликовано:	American Society for Microbiology (ASM) 1999
Предметы:	Gene Therapy
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC103924/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9882305/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.2.1046-1053.1999
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