Potent inhibition of Werner and Bloom helicases by DNA minor groove binding drugs
Maintenance of genomic integrity is vital to all organisms. A number of human genetic disorders, including Werner Syndrome, Bloom Syndrome and Rothmund–Thomson Syndrome, exhibit genomic instability with some phenotypic characteristics of premature aging and cancer predisposition. Presumably the aber...
Kaydedildi:
| Yayımlandı: | Nucleic Acids Res |
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| Asıl Yazarlar: | , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Oxford University Press
2000
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC102731/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10871376/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/28.12.2420 |
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