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The Bloom’s syndrome helicase stimulates the activity of human topoisomerase IIIα

Bloom’s syndrome (BS) is a disorder associated with chromosomal instability and a predisposition to the development of cancer. The BS gene product, BLM, is a DNA helicase of the RecQ family that forms a complex in vitro and in vivo with topoisomerase IIIα. Here, we show that BLM stimulates the abili...

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Bibliografski detalji
Glavni autori: Wu, Leonard, Hickson, Ian D.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2002
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC137159/
https://ncbi.nlm.nih.gov/pubmed/12433984
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