The Bloom’s syndrome helicase stimulates the activity of human topoisomerase IIIα
Bloom’s syndrome (BS) is a disorder associated with chromosomal instability and a predisposition to the development of cancer. The BS gene product, BLM, is a DNA helicase of the RecQ family that forms a complex in vitro and in vivo with topoisomerase IIIα. Here, we show that BLM stimulates the abili...
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| Опубликовано в:: | Nucleic Acids Res |
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| Главные авторы: | , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
2002
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC137159/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12433984/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkf611 |
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