Potent inhibition of Werner and Bloom helicases by DNA minor groove binding drugs

Maintenance of genomic integrity is vital to all organisms. A number of human genetic disorders, including Werner Syndrome, Bloom Syndrome and Rothmund–Thomson Syndrome, exhibit genomic instability with some phenotypic characteristics of premature aging and cancer predisposition. Presumably the aber...

Täydet tiedot

Bibliografiset tiedot

Julkaisussa:	Nucleic Acids Res
Päätekijät:	Brosh Jr, Robert M., Karow, Julia K., White, E. James, Shaw, Natalie D., Hickson, Ian D., Bohr, Vilhelm A.
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	Oxford University Press 2000
Aiheet:	Article
Linkit:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC102731/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10871376/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/28.12.2420
Tagit:	Lisää tagi Ei tageja, Lisää ensimmäinen tagi!