Loading...
Formaldehyde activation of mitoxantrone yields CpG and CpA specific DNA adducts
Recently we have found that mitoxantrone, like Adriamycin, can be activated by formaldehyde and subsequently form adducts which stabilise double-stranded DNA in vitro. This activation by formaldehyde may be biologically relevant since formaldehyde levels are elevated in those tumours in which mitoxa...
Na minha lista:
| Main Authors: | , , , |
|---|---|
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2000
|
| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC102576/ https://ncbi.nlm.nih.gov/pubmed/10648792 |
| Tags: |
Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!
|