Genomic Targeting of Methylated DNA: Influence of Methylation on Transcription, Replication, Chromatin Structure, and Histone Acetylation

We have developed a strategy to introduce in vitro-methylated DNA into defined chromosomal locations. Using this system, we examined the effects of methylation on transcription, chromatin structure, histone acetylation, and replication timing by targeting methylated and unmethylated constructs to ma...

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Main Authors: Schübeler, Dirk, Lorincz, Matthew C., Cimbora, Daniel M., Telling, Agnes, Feng, Yong-Quing, Bouhassira, Eric E., Groudine, Mark
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2000
主題:
Gene Expression
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC102168/
https://ncbi.nlm.nih.gov/pubmed/11094062
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