DNA Methylation Density Influences the Stability of an Epigenetic Imprint and Dnmt3a/b-Independent De Novo Methylation

DNA methylation plays an important role in transcriptional repression. To gain insight into the dynamics of demethylation and de novo methylation, we introduced a proviral reporter, premethylated at different densities, into a defined chromosomal site in murine erythroleukemia cells and monitored th...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Lorincz, Matthew C., Schübeler, Dirk, Hutchinson, Shauna R., Dickerson, David R., Groudine, Mark
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 2002
Assuntos:	Transcriptional Regulation
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC135678/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12370304/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.22.21.7572-7580.2002
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