Methylation-Mediated Proviral Silencing Is Associated with MeCP2 Recruitment and Localized Histone H3 Deacetylation

The majority of 5-methylcytosine in mammalian DNA resides in endogenous transposable elements and is associated with the transcriptional silencing of these parasitic elements. Methylation also plays an important role in the silencing of exogenous retroviruses. One of the difficulties inherent in the...

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Bibliografiska uppgifter
Huvudupphovsmän: Lorincz, Matthew C., Schübeler, Dirk, Groudine, Mark
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2001
Ämnen:
Transcriptional Regulation
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC99960/
https://ncbi.nlm.nih.gov/pubmed/11689684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.23.7913-7922.2001
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