Genomic Targeting of Methylated DNA: Influence of Methylation on Transcription, Replication, Chromatin Structure, and Histone Acetylation

We have developed a strategy to introduce in vitro-methylated DNA into defined chromosomal locations. Using this system, we examined the effects of methylation on transcription, chromatin structure, histone acetylation, and replication timing by targeting methylated and unmethylated constructs to ma...

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Detalhes bibliográficos
Main Authors: Schübeler, Dirk, Lorincz, Matthew C., Cimbora, Daniel M., Telling, Agnes, Feng, Yong-Quing, Bouhassira, Eric E., Groudine, Mark
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2000
Assuntos:
Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC102168/
https://ncbi.nlm.nih.gov/pubmed/11094062
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