Genomic Targeting of Methylated DNA: Influence of Methylation on Transcription, Replication, Chromatin Structure, and Histone Acetylation

We have developed a strategy to introduce in vitro-methylated DNA into defined chromosomal locations. Using this system, we examined the effects of methylation on transcription, chromatin structure, histone acetylation, and replication timing by targeting methylated and unmethylated constructs to ma...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Schübeler, Dirk, Lorincz, Matthew C., Cimbora, Daniel M., Telling, Agnes, Feng, Yong-Quing, Bouhassira, Eric E., Groudine, Mark
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 2000
Assuntos:	Gene Expression
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC102168/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11094062/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.24.9103-9112.2000
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