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Genomic Targeting of Methylated DNA: Influence of Methylation on Transcription, Replication, Chromatin Structure, and Histone Acetylation

We have developed a strategy to introduce in vitro-methylated DNA into defined chromosomal locations. Using this system, we examined the effects of methylation on transcription, chromatin structure, histone acetylation, and replication timing by targeting methylated and unmethylated constructs to ma...

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Vydáno v:Mol Cell Biol
Hlavní autoři: Schübeler, Dirk, Lorincz, Matthew C., Cimbora, Daniel M., Telling, Agnes, Feng, Yong-Quing, Bouhassira, Eric E., Groudine, Mark
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2000
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC102168/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11094062/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.24.9103-9112.2000
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